374Water, Inc. is a social impact, clean tech company, which offers an innovative technology that enables a circular economy and creation of a world without waste.

Greenlight Ready

In partnership with the City and County of Durham and Duke Health, Greenlight Ready provides COVID-19 monitoring, guidance, and testing access to businesses in Durham.

Sparta Biomedical

Sparta Biomedical is a developer of orthopedic solutions. The company’s SBM-01 Biomimetic Implant has been granted a Breakthrough Device Designation from the FDA.

Cohere Med

Cohere Med, Inc., is a clinical analytics company which strives to provide predictive solutions to clinicians to help improve clinical outcomes and reduce cost of healthcare.

Basking Biosciences

Basking Biosciences is developing the first reversible thrombolytic therapy for acute ischemic stroke (AIS).

Eclipse Life Sciences

Eclipse Life Sciences is developing therapeutic compounds to treat ophthalmological disease.


ZealCare aims to improve the health and well-being of people with complex chronic diseases.


Mente is developing a surgical instruments tracking system for the operating room which creates dependable, real-time data streams with predictive analytics to transform operating room resource management.

HealthForceRx (SBV HF)

HealthForcesRxS (BV HF ) is commercializing innovation developed by the Duke Heart Center.


The company aims to create spin-out companies that will commercialize therapeutics and biomarkers for neuropsychiatric disorders and diseases.

Splendo Health

The company has developed SplendoFit, a comprehensive digital platform for remote healthcare monitoring, communication, and intervention.

Replicate Bioscience

Replicate Bioscience is developing RNA-based treatments for cancer using proprietary Synthetic Replicon for gene delivery (SynRGY) technology to deliver the genetic code of a virally derived RNA molecule.

Roke Biotechnologies

Roke Biotechnologies aims to commercialized novel 2-stage protein expression and purification technologies.